February 15, 2022 Uncategorized No Comments

ATIVAN (LORAZEPAM)

Ativan is a well-known drug from the group of benzodiazepine derivatives, that are widely used for the remedy of a large spectrum of psychological well being issues from sleeping disorders to epileptic seizures. According to the directions for use, Ativan also has a relaxing and relaxing impact.

The drug is relevant for neurosis and anxiety states accompanied by somatic issues, insomnia and panic assaults. It additionally has an anticonvulsant and muscle relaxant impact.

PHARMACODYNAMICS AND PHARMACOKINETICS

Pharmachologic impact of Lorazepam is due to its similarity with gamma-aminobutyric acid (GABA). Lorazepam belongs to the category of benzodiazepine derivatives and impacts the CNS constructions, liable for the regulation of emotional activity (these are limbic system and hypothalamus). The drug supplies the circulate of chlorine into the excited neuron, which in flip stabilizes neuron.

  • anxiolytic
  • sleeping drug
  • anticonvulsant
  • muscle relaxant

Active substance is properly absorbed from the digestive tract, reaching its most concentration within the patient’s blood 2 hours later.

INDICATIONS AND CONTRAINDICATIONS

Ativan is widely used within the trendy drugs for the treatment of such states and mental sicknesses:

  • psychosis
  • various phobias
  • psychosomatic disorders
  • epilepsy
  • panic attacks
  • obsessive-compulsive syndrome
  • mental problems associated to injuries
  • behavioral disorders
  • sleep disorders
  • headache attributable to increased emotional stress and tension
  • nervousness and anxiety
  • consequences of the shock experienced
  • sickness and vomiting, triggered by a course of chemotherapy

Also, Ativan can be used as a component of mixture remedy during the therapy of chronic alcohol habit. Sometimes, it is prescribed together with analgesic medicines to arrange the patients for operative or diagnostic interventions.

Ativan is utilized in medication to get rid of the signs of mental illnesses:

  • nervousness
  • increased anxiety
  • tremor
  • insomnia
  • psychosis
  • alcohol delirium
  • cramps
  • paralysis
  • athetosis

Ativan is a strong substance; due to this fact, it’s strictly forbidden to the sufferers, which have the next concomitant illnesses and conditions:

  • hypersensitivity to the active substance or auxiliary components
  • intolerance to other medicine with an identical mechanism of action
  • myasthenia
  • glaucoma
  • intoxication with substances miserable the central nervous system
  • breathing problems
  • liver failure
  • apnea syndrome
  • depression
  • addiction to medicine, nicotine and alcohol (except withdrawal syndrome)
  • alcohol intoxication
  • acute renal failure

The use of Ativan is strictly forbidden to pregnant and breastfeeding ladies. If the usage of Lorazepam is crucial for the mother’s health, she should cease breastfeeding for the time of remedy with this medicine. Also, this treatment is forbidden to the minor patients. Elderly patients must take Lorazepam with great caution and intently monitor the body’s response to the drug.

The use of Ativan can affect the patient’s response price. Therefore, in the course of the remedy, you should refrain from driving and managing other complicated mechanisms and limit the work requiring caution.

DOSAGE

According to the instructions to be used, you must start the therapy with Ativan with the bottom effective dose, and the course must not be long. With a large dosage and long course, such substances can make the patient addicted. In case of abrupt withdrawal of Ativan, likelihood is that the patient may expertise withdrawal or rebound syndrome; due to this fact, it is essential to cease the course by gradually decreasing the drug dose.

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